Scion: Hero is my favorite RPG ever. The system is brilliant and works wonderfully for this level of gameplay. Admittedly, the system seems to break down a bit once you reach Demigod and God (primarily in regards to the game balance of epic dexterity, in my opinion), but the game is brilliant enough that it doesn't seem that big of a deal.
White Wolf/ Onyx Path does a brilliant job of creating settings in most of their work because they do a lot of research into the subjects. They didn't just throw a couple of pantheons together and make up some stories for them, they dug into the actual mythology from various cultures and put it all in a meta-narrative. As I said at the beginning, this is my favorite RPG ever, and I've played a large number of systems and settings.
[5 of 5 Stars!]