I thoroughly enjoyed reading through this campaign. I don't know when I'll ever get to run it, or if my brain/SAN rating could even handle doing so. I'm looking forward to the day when I can try my hand at putting some unsuspecting players through it. Definitely not a "pick up the book and start playing"-type campaign. It is too deep for that. But the work you put into running and playing it will pay off.
And either way, Impossible Landscapes is worth getting just for the joy of reading it. Dennis and Arc Dream have put years of work into this campaign, and it shows. From the artwork to the evocative, reality-bending writing and scenario design. If you and your group are up for it, I'm sure it would be a terrifying ride.