Bride of Portable Hole is a fun little magazine, so long as you understand from the beginning that it's meant to be humorous rather than effective. It contains a large number of articles that give you everything from prestige classes to stats for the legendary Gazebo (which is apparently quite a tough monster now). It's theoretically possible that you could gain some usage from the gaming options in here, but in reality you're better suited just reading it for the laughs (of which there are a fair number.) I have dabbled with the idea of the "magic user" class (a class that allows you to use and manipulate a far greater number of magic items than normal), but even they admit that that's not a very playable class (though they do have a few playable classes that, if you take them seriously, might be worthwhile.)

Ultimately, the best use of this book at the game table is as a creative stimulant which could help you to think outside of the box for your own game. And you never know, maybe you'll find an overlooked monster or spell in here that, under the right circumstances, will be exactly what you need...